In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab–MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios
Author:
Affiliation:
1. PolyTherics Ltd. and ‡Antitope Ltd., Abzena, Babraham Research Campus, CB22 3AT Cambridge, United Kingdom
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00116
Reference29 articles.
1. Monoclonal antibody successes in the clinic
2. Antibody therapy of cancer
3. HER2 Amplification Ratios by Fluorescence In Situ Hybridization and Correlation with Immunohistochemistry in a Cohort of 6556 Breast Cancer Tissues
4. Strategies to overcome trastuzumab resistance in HER2-overexpressing breast cancers: focus on new data from clinical trials
5. Rituximab (monoclonal anti-CD20 antibody): mechanisms of action and resistance
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