Improvement in Inhalation Properties of Theophylline and Levofloxacin by Co-Amorphization and Enhancement in Its Stability by Addition of Amino Acid as a Third Component-Reference-Cited by-同舟云学术

Improvement in Inhalation Properties of Theophylline and Levofloxacin by Co-Amorphization and Enhancement in Its Stability by Addition of Amino Acid as a Third Component

Published:2023-11-09 Issue:12 Volume:20 Page:6368-6379
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Ueda Hiroshi¹^ORCID,Hirakawa Yuya¹^ORCID,Miyano Tetsuya²,Nakayama Yuzuki³,Hatanaka Yuta³,Uchiyama Hiromasa³,Tozuka Yuichi³^ORCID,Kadota Kazunori³^ORCID

Affiliation:

1. Analysis and Evaluation Laboratory, Shionogi & Co., Ltd., Osaka 561-0825, Japan

2. Laboratory for Medicinal Chemistry Research, Shionogi & Co., Ltd., Osaka 561-0825, Japan

3. Department of Formulation Design and Pharmaceutical Technology, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, Osaka 569-1094, Japan

Funder

Hosokawa Powder Technology Foundation

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00756

Reference71 articles.

1. Supersaturation and phase behavior during dissolution of amorphous solid dispersions

2. Recent Advances in Amorphous Solid Dispersions: Preformulation, Formulation Strategies, Technological Advancements and Characterization

3. New Development in Understanding Drug–Polymer Interactions in Pharmaceutical Amorphous Solid Dispersions from Solid-State Nuclear Magnetic Resonance

4. Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs

5. Solid dispersions: a strategy for poorly aqueous soluble drugs and technology updates

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