Confocal Raman Spectroscopic Characterization of Dermatopharmacokinetics Ex Vivo

Author:

Zarmpi Panagiota1,Tabosa M. Alice Maciel1,Vitry Pauline1,Bunge Annette L.2ORCID,Belsey Natalie A.34ORCID,Tsikritsis Dimitrios3,Woodman Timothy J.1,Delgado-Charro M. Begoña1,Guy Richard H.1ORCID

Affiliation:

1. Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, U.K.

2. Department of Chemical & Biological Engineering, Colorado School of Mines, Golden, Colorado 80401, United States

3. National Physical Laboratory, Teddington TW11 0LW, U.K.

4. School of Chemistry & Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.

Funder

U.S. Food and Drug Administration

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference31 articles.

1. Guidance for Industry: Bioavailability and Bioequivalence Studies Submitted in NDAs or INDs ─ General Considerations. https://www.fda.gov/files/drugs/published/Bioavailability-and-Bioequivalence-Studies-Submitted-in-NDAs-or-INDs-%E2%80%94-General-Considerations.pdf (accessed 17 Jan, 2023).

2. Pharmacokinetics-Based Approaches for Bioequivalence Evaluation of Topical Dermatological Drug Products

3. Quantification of Chemical Uptake into the Skin by Vibrational Spectroscopies and Stratum Corneum Sampling

4. In Vivo Confocal Raman Microspectroscopy of the Skin: Noninvasive Determination of Molecular Concentration Profiles

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