Synthesis and Characterization of Cetuximab–Docetaxel and Panitumumab–Docetaxel Antibody–Drug Conjugates for EGFR-Overexpressing Cancer Therapy-Reference-Cited by-同舟云学术

Synthesis and Characterization of Cetuximab–Docetaxel and Panitumumab–Docetaxel Antibody–Drug Conjugates for EGFR-Overexpressing Cancer Therapy

Published:2018-09-18 Issue:11 Volume:15 Page:5089-5102
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Glatt Dylan M.¹^ORCID,Beckford Vera Denis R.²,Prabhu Shamit S.¹,Mumper Russell J.¹,Luft J. Christopher¹,Benhabbour S. Rahima¹³^ORCID,Parrott Matthew C.²

Affiliation:

1. Division of Pharmacoengineering and Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 125 Mason Farm Road, Chapel Hill, North Carolina 27599, United States

2. Department of Radiology, Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Marsico Hall, 125 Mason Farm Road, Chapel Hill, North Carolina 27599, United States

3. UNC-NCSU Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Marsico Hall, 125 Mason Farm Road, Chapel Hill, North Carolina 27599, United States

Funder

National Center for Advancing Translational Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00672

Reference59 articles.

1. Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

2. Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics

3. A Wortmannin−Cetuximab as a Double Drug

4. Studies With RP 56976 (Taxotere): A Semisynthetic Analogue of Taxol

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