Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug–Polymer Interactions
Author:
Affiliation:
1. Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States
2. Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, United States
Funder
Bill and Melinda Gates Foundation
IPEC-Americas Foundation
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00481
Reference56 articles.
1. Pharmaceutical applications of cyclodextrins: basic science and product development
2. Bioavailability of Lumefantrine Is Significantly Enhanced with a Novel Formulation Approach, an Outcome from a Randomized, Open-Label Pharmacokinetic Study in Healthy Volunteers
3. Coartem®: the journey to the clinic
4. Clinical Pharmacokinetics and Pharmacodynamics of Artemether-Lumefantrine
5. How much fat is necessary to optimize lumefantrine oral bioavailability?
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