Evaluation of Copper-64-Labeled αvβ6-Targeting Peptides: Addition of an Albumin Binding Moiety to Improve Pharmacokinetics-Reference-Cited by-同舟云学术

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Evaluation of Copper-64-Labeled αvβ6-Targeting Peptides: Addition of an Albumin Binding Moiety to Improve Pharmacokinetics

Published:2021-11-16 Issue:12 Volume:18 Page:4437-4447
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Ganguly Tanushree¹^ORCID,Bauer Nadine²,Davis Ryan A.¹^ORCID,Hausner Sven H.²,Tang Sarah Y.²,Sutcliffe Julie L.¹²³

Affiliation:

1. Department of Biomedical Engineering, University of California Davis, Sacramento, California 95817, United States

2. Department of Internal Medicine, Division of Hematology/Oncology, University of California Davis, Sacramento, California 95817, United States

3. Center for Molecular and Genomic Imaging, University of California Davis, Sacramento, California 95817, United States

Funder

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00632

Reference51 articles.

1. Overexpression of αvβ6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade

2. Defining the Role of Integrin αvβ6 in Cancer

3. Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma

4. Expression of αv Integrin Family in Gastric Carcinomas: Increased αvβ6 is Associated with Lymph Node Metastasis

5. The roles of integrin αvβ6 in cancer

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5. Preclinical Evaluation of⁶⁸Ga- and¹⁷⁷Lu-Labeled Integrin α_vβ₆-Targeting Radiotheranostic Peptides;Journal of Nuclear Medicine;2022-10-07

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