Ocular Half-Life of Intravitreal Biologics in Humans and Other Species: Meta-Analysis and Model-Based Prediction-Reference-Cited by-同舟云学术

Ocular Half-Life of Intravitreal Biologics in Humans and Other Species: Meta-Analysis and Model-Based Prediction

Published:2020-01-16 Issue: Volume: Page:
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Caruso Antonello¹^ORCID,Füth Matthias¹,Alvarez-Sánchez Ruben¹^ORCID,Belli Sara¹,Diack Cheikh¹,Maass Katie F.²,Schwab Dietmar¹,Kettenberger Hubert³,Mazer Norman A.¹^ORCID

Affiliation:

1. Pharmaceutical Sciences, Roche Innovation Center Basel, Roche Pharma Research and Early Development, Basel 4070, Switzerland

2. Clinical Pharmacology, Genentech, South San Francisco 94080, California, United States

3. Therapeutic Modalities, Roche Innovation Center Munich, Roche Pharma Research and Early Development, Penzberg 82377, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b01191

Reference87 articles.

1. Evaluating Patient Discomfort, Anxiety, and Fear Before and After Ranibizumab Intravitreous Injection for Wet Age-Related Macular Degeneration

2. TUNNELLED VERSUS STRAIGHT INTRAVITREAL INJECTION

3. Intravitreal Aflibercept Injection for Neovascular Age-related Macular Degeneration

4. Brolucizumab Versus Aflibercept in Participants with Neovascular Age-Related Macular Degeneration: A Randomized Trial

5. A Mechanistic Model of the Intravitreal Pharmacokinetics of Large Molecules and the Pharmacodynamic Suppression of Ocular Vascular Endothelial Growth Factor Levels by Ranibizumab in Patients with Neovascular Age-Related Macular Degeneration

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