Prediction of Liquid–Liquid Phase Separation at the Dissolving Drug Salt Particle Surface
Author:
Affiliation:
1. Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga 525-8577, Japan
Funder
Japan Science and Technology Agency
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00157
Reference46 articles.
1. Solubility and Dissolution Profile Assessment in Drug Discovery
2. Salt formation to improve drug solubility
3. Establishment of new preparation method for solid dispersion formulation of tacrolimus
4. Impact of the Dissolution Profile of the Cilostazol Cocrystal with Supersaturation on the Oral Bioavailability
5. Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
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