Brain Targeting of a Water Insoluble Antipsychotic Drug Haloperidol via the Intranasal Route Using PAMAM Dendrimer-Reference-Cited by-同舟云学术

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Brain Targeting of a Water Insoluble Antipsychotic Drug Haloperidol via the Intranasal Route Using PAMAM Dendrimer

Published:2015-08-24 Issue:9 Volume:12 Page:3380-3388
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Katare Yogesh K.¹,Daya Ritesh P.¹,Sookram Gray Christal¹,Luckham Roger E.²,Bhandari Jayant¹,Chauhan Abhay S.³,Mishra Ram K.¹

Affiliation:

1. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada

2. Department of Chemistry, McMaster University, Hamilton, Ontario L8S 4M1, Canada

3. School of Pharmacy, Concordia University Wisconsin, Mequon, Wisconsin 53097, United States

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00402

Reference36 articles.

1. The blood-brain barrier: Bottleneck in brain drug development

2. Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

3. Delivery of Neurotrophic Factors to the Central Nervous System

4. Intranasal “painless” Human Nerve Growth Factors Slows Amyloid Neurodegeneration and Prevents Memory Deficits in App X PS1 Mice

5. Physicochemical and physiological considerations for efficient nose-to-brain targeting

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