In Situ Salt Formation during Melt Extrusion for Improved Chemical Stability and Dissolution Performance of a Meloxicam–Copovidone Amorphous Solid Dispersion-Reference-Cited by-同舟云学术

In Situ Salt Formation during Melt Extrusion for Improved Chemical Stability and Dissolution Performance of a Meloxicam–Copovidone Amorphous Solid Dispersion

Published:2018-02-07 Issue:3 Volume:15 Page:1226-1237
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Haser Abbe¹,Cao Tu¹,Lubach Joseph W.²^ORCID,Zhang Feng¹^ORCID

Affiliation:

1. Division of Pharmaceutics, College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, A1920, Austin, Texas 78712, United States

2. Genentech, 1 DNA Way, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b01057

Reference52 articles.

1. Pharmaceutical applications of cyclodextrins: basic science and product development

2. Improving drug solubility for oral delivery using solid dispersions

3. Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

4. Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A Review

5. Theoretical and Practical Approaches for Prediction of Drug–Polymer Miscibility and Solubility

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