Gastrointestinal and Systemic Disposition of Diclofenac under Fasted and Fed State Conditions Supporting the Evaluation of in Vitro Predictive Tools-Reference-Cited by-同舟云学术

Gastrointestinal and Systemic Disposition of Diclofenac under Fasted and Fed State Conditions Supporting the Evaluation of in Vitro Predictive Tools

Published:2017-07-07 Issue:12 Volume:14 Page:4220-4232
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Van Den Abeele Jens¹,Schilderink Ronald²³,Schneider Felix⁴,Mols Raf¹,Minekus Mans²³,Weitschies Werner⁴,Brouwers Joachim¹,Tack Jan⁵,Augustijns Patrick¹^ORCID

Affiliation:

1. Drug Delivery and Disposition, KU Leuven, Gasthuisberg O&N II, Herestraat 49, Box 921, 3000 Leuven, Belgium

2. TNO, P.O. 360, 3700 AJ, Zeist, The Netherlands

3. Triskelion B.V., P.O. Box 844, 3700 AV Zeist, The Netherlands

4. Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Felix-Hausdorff-Straße 3, 17489 Greifswald, Germany

5. Translational Research Center for Gastrointestinal Disorders (TARGID), KU Leuven, Herestraat 49, 3000 Leuven, Belgium

Funder

Fonds Wetenschappelijk Onderzoek

Innovative Medicines Initiative

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b00253

Reference37 articles.

1. In vitro models for the prediction of in vivo performance of oral dosage forms