A Challenging Synthesis of the Highly Functionalized Echinocandin ASP9726: A Successor of Micafungin-Reference-Cited by-同舟云学术

A Challenging Synthesis of the Highly Functionalized Echinocandin ASP9726: A Successor of Micafungin

Published:2014-05-13 Issue:6 Volume:18 Page:725-738
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Yoshida Shinya¹,Hayashida Joji¹,Morinaga Yasuhiro¹,Mizobata Shoji¹,Okada Akihiro²,Kawai Kazumi³,Tanoue Shinjirou³,Nakata Tomohide¹,Kitayama Minoru³,Ohigashi Atsushi¹,Matsuura Mitsutaka³,Takahashi Takumi⁴,Ieda Shigeru¹,Okada Minoru¹

Affiliation:

1. Process Chemistry Labs., Astellas Pharma Inc., 160-2 Akahama, Takahagi-shi, Ibaraki 318-0001, Japan

2. Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan

3. Fermentation and Biotechnology Labs., Astellas Pharma Inc., 5-2-3, Tokodai, Tsukuba-shi, Ibaraki 300-2698, Japan

4. Technology Product Management, Astellas Pharma Inc., 2-5-1, Nihonbashi-Honcho, Chuo-ku, Tokyo, 103-8411, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op500078y

Reference32 articles.

1. In Vitro Activities of a New Lipopeptide Antifungal Agent, FK463, against a Variety of Clinically Important Fungi

2. Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Disseminated Candidiasis and Aspergillosis

3. Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Pulmonary Aspergillosis

4. Antifungal Mechanism of FK463 against Candida albicans and Aspergillus fumigatus.

5. FK463, a Novel Water-soluble Echinocandin Lipopeptide. Synthesis and Antifungal Activity.

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2. A Challenging Synthesis of the Highly Functionalized Echinocandin ASP9726: A Successor of Micafungin—How Can We Achieve the Large-Scale Synthesis?;New Horizons of Process Chemistry;2017

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