6-Anilinouracil-Based Inhibitors of Bacillus subtilis DNA Polymerase III: Antipolymerase and Antimicrobial Structure−Activity Relationships Based on Substitution at Uracil N3-Reference-Cited by-同舟云学术

6-Anilinouracil-Based Inhibitors of Bacillus subtilis DNA Polymerase III: Antipolymerase and Antimicrobial Structure−Activity Relationships Based on Substitution at Uracil N3

Published:1999-05-07 Issue:11 Volume:42 Page:2035-2040
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tarantino, Paul M.¹,Zhi Chengxin¹,Gambino Joseph J.¹,Wright George E.¹,Brown Neal C.¹

Affiliation:

1. Department of Pharmacology and Molecular Toxicology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, and GLSynthesis, Inc., 222 Maple Avenue, Shrewsbury, Massachusetts 01545

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980693i

Reference25 articles.

1. Multiple-Antibiotic-Resistant Pathogenic Bacteria -- A Report on the Rockefeller University Workshop

2. Mutational alteration of DNA polymerase III to hydroxyphenylazopyrimidine resistance: Polymerase III is necessary for DNA replication

3. Hydroxyphenylazopyrimidines: Characterization of the Active Forms and Their Inhibitory Action on a DNA Polymerase from Bacillus subtilis

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