In Vitro and in Vivo Characterization of 3-{2-[6-(2-tert-Butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl}benzonitrile Hydrochloride Salt, a Potent and Selective NPY5 Receptor Antagonist-Reference-Cited by-同舟云学术

In Vitro and in Vivo Characterization of 3-{2-[6-(2-tert-Butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl}benzonitrile Hydrochloride Salt, a Potent and Selective NPY5 Receptor Antagonist

Published:2003-02-01 Issue:5 Volume:46 Page:670-673
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Elliott Richard L.¹,Oliver Robert M.¹,Hammond Marlys¹,Patterson Terrell A.¹,She Li¹,Hargrove Diane M.¹,Martin Kelly A.¹,Maurer Tristan S.¹,Kalvass J. Cory¹,Morgan Bradley P.¹,DaSilva-Jardine Paul A.¹,Stevenson Ralph W.¹,Mack Christine M.¹,Cassella James V.¹

Affiliation:

1. Cardiovascular and Metabolic Diseases, PGRD, Pfizer Inc., Groton, Connecticut 06340, and Neurogen Corporation, Branford, Connecticut 06405

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm025584p

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4. Central administration of Y5 receptor antisense decreases spontaneous food intake and attenuates feeding in response to exogenous neuropeptide Y

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