wALADin Benzimidazoles Differentially Modulate the Function of Porphobilinogen Synthase Orthologs-Reference-Cited by-同舟云学术

wALADin Benzimidazoles Differentially Modulate the Function of Porphobilinogen Synthase Orthologs

Published:2014-02-25 Issue:6 Volume:57 Page:2498-2510
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lentz Christian S.¹,Halls Victoria S.²,Hannam Jeffrey S.²,Strassel Silke¹,Lawrence Sarah H.³,Jaffe Eileen K.³,Famulok Michael²,Hoerauf Achim¹,Pfarr Kenneth M.¹

Affiliation:

1. Institute of Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Sigmund-Freud Strasse 25, 53127 Bonn, Germany

2. Chemical Biology and Medicinal Chemistry Unit, LIMES Institute, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany

3. Fox Chase Cancer Center, Temple University Health System, 333 Cottman Avenue, Philadelphia, Pennsylvania, 19111, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401785n

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5. The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target

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