Syntheses and thymidylate synthase inhibitory activity of the poly-.gamma.-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolates-Reference-Cited by-同舟云学术

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Syntheses and thymidylate synthase inhibitory activity of the poly-.gamma.-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolates

Published:1992-03 Issue:5 Volume:35 Page:859-866
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bisset Graham M. F.,Pawelczak Krzysztof,Jackman Ann L.,Calvert A. Hilary,Hughes Leslie R.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm00083a008

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3. Synthesis and reactions ofn-methyl-4-(methylthio)thieno[2,3-d]-pyrimidinium salts;Journal of Heterocyclic Chemistry;2008-09

4. References;Chemistry of Heterocyclic Compounds: A Series Of Monographs;2008-01-02

5. Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumor Agents: Design, Synthesis, and Biological Evaluation of Classical and Nonclassical Pyrrolo[2,3-d]pyrimidine Antifolates;Journal of Medicinal Chemistry;2006-01-12

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