Facile and Adaptable Synthesis of a Prazosin Analogue Library: Bringing Medicinal Chemistry into the Undergraduate Curriculum-Reference-Cited by-同舟云学术

Facile and Adaptable Synthesis of a Prazosin Analogue Library: Bringing Medicinal Chemistry into the Undergraduate Curriculum

Published:2022-02-22 Issue:3 Volume:99 Page:1428-1434
ISSN:0021-9584
Container-title:Journal of Chemical Education
language:en
Short-container-title:J. Chem. Educ.

Author:

Milicaj Jozafina¹,Dodda Vasudeva R.²,Patel Kaelan R.²³,Aragon Ingrid Rodriguez³⁴,O’Connell Timothy³,Muthyala Ramaiah²,Taylor Erika A.¹^ORCID,Sham Yuk Y.³⁴

Affiliation:

1. Department of Chemistry, Wesleyan University, Middletown, Connecticut 06459, United States

2. Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, United States

3. Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota 55455, United States

4. Bioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, Minnesota 55455, United States

Publisher

American Chemical Society (ACS)

Subject

Education,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jchemed.1c00822

Reference20 articles.

1. Synthesis of Aspirin: A General Chemistry Experiment

2. Expanding the medicinal chemistry synthetic toolbox

3. Retrosynthetic Analysis

4. Robert Robinson Lecture. Retrosynthetic thinking—essentials and examples

5. Structure-activity relationships in prazosin-related compounds. 2. Role of the piperazine ring on .alpha.-blocking activity

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