Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands-Reference-Cited by-同舟云学术

Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands

Published:1996-01-01 Issue:18 Volume:39 Page:3435-3450
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Campiani Giuseppe¹,Nacci Vito¹,Fiorini Isabella¹,De Filippis Maria P.¹,Garofalo Antonio¹,Ciani Silvia M.¹,Greco Giovanni¹,Novellino Ettore¹,Williams D. Clive¹,Zisterer Daniela M.¹,Woods Margaret J.¹,Mihai Camelia¹,Manzoni Cristina¹,Mennini Tiziana¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico, Universita' di Siena, Banchi di Sotto 55, 53100 Siena, Italy, Istituto di Ricerche Farmacologiche “Mario Negri”, via Eritrea 62, 40126 Milano, Italy, Department of Biochemistry, Trinity College, Dublin 2, Ireland, and Dipartimento di Chimica Farmaceutica e Tossicologica, Universita' di Napoli “Federico II”, via D. Montesano 49, 80131 Napoli, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960251b

Reference69 articles.

1. Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

2. High affinity renal [3H]flunitrazepam binding: Characterization, localization, and alteration in hypertension

3. Specific high-affinity saturable binding of [3H] Ro5-4864 To benzodiazepine binding sites in the rat cerebral cortex

4. Molecular Mechanisms in the Receptor Action of Benzodiazepines

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