α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling: Insight from Environmentally Coupled Tunneling Models-Reference-Cited by-同舟云学术

α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling: Insight from Environmentally Coupled Tunneling Models

Published:2006-10-05 Issue:43 Volume:128 Page:14053-14058
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Pudney Christopher R.¹,Hay Sam¹,Sutcliffe Michael J.¹,Scrutton Nigel S.¹

Affiliation:

1. Contribution from the Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, and School of Chemical Engineering and Analytical Science, University of Manchester, 131 Princess Street, Manchester M1 7ND, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja0614619

Reference48 articles.

1. Tunneling in proton-transfer reactions in solution

2. Large kinetic isotope effects in enzymatic proton transfer and the role of substrate oscillations

3. How Enzymes Work: Analysis by Modern Rate Theory and Computer Simulations

4. Vibrationally enhanced tunneling as a mechanism for enzymatic hydrogen transfer

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