Transannular Functionalization of Multiple C(sp<sup>3</sup>)–H Bonds of Tropane via an Alkene-Bridged Palladium(I) Dimer-Reference-Cited by-同舟云学术

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Transannular Functionalization of Multiple C(sp³)–H Bonds of Tropane via an Alkene-Bridged Palladium(I) Dimer

Published:2023-04-10 Issue:8 Volume:42 Page:627-631
ISSN:0276-7333
Container-title:Organometallics
language:en
Short-container-title:Organometallics

Author:

Aguilera Ellen Y.¹,Liu En-Chih¹,Thullen Scott M.¹,Sanford Melanie S.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States

Funder

Horace H. Rackham School of Graduate Studies, University of Michigan

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.organomet.3c00086

Reference67 articles.

1. Rings in Drugs

2. bQureshi, M. H.; Smith, D. T.; Delost, M. D.; Njardarson, J. T. Top 200 Pharmaceutical Products by Prescription in 2016. University of Arizona, 2016. http://njardarson.lab.arizona.edu/sites/njardarson.lab.arizona.edu/files/2016Top200PharmaceuticalPrescriptionSalesPosterLowResV2.pdf (accessed January 2023).

3. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

4. Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

5. C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

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