Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate-Reference-Cited by-同舟云学术

Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate

Published:2007-02-02 Issue:5 Volume:50 Page:897-900
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Slater Martin J.¹,Amphlett Elizabeth M.¹,Andrews David M.¹,Bravi Gianpaolo¹,Burton George¹,Cheasty Anne G.¹,Corfield John A.¹,Ellis Malcolm R.¹,Fenwick Rebecca H.¹,Fernandes Stephanie¹,Guidetti Rossella¹,Haigh David¹,Hartley C. David¹,Howes Peter D.¹,Jackson Deborah L.¹,Jarvest Richard L.¹,Lovegrove Victoria L. H.¹,Medhurst Katrina J.¹,Parry Nigel R.¹,Price Helen¹,Shah Pritom¹,Singh Onkar M. P.¹,Stocker Richard¹,Thommes Pia¹,Wilkinson Claire¹,Wonacott Alan¹

Affiliation:

1. Infectious Diseases CEDD and Medicinal Discovery Research, GlaxoSmithKline, GSK Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061207r

Reference28 articles.

1. Developments in hepatitis C therapy during 2000 – 2002

2. Relation of hepatitis C virus to hepatocellular carcinoma

3. Dose-finding study of interferon alfa-n3 in hepatitis

4. Hepatitis C

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