Rapid Generation of a High Quality Lead for Transforming Growth Factor-β (TGF-β) Type I Receptor (ALK5)-Reference-Cited by-同舟云学术

Rapid Generation of a High Quality Lead for Transforming Growth Factor-β (TGF-β) Type I Receptor (ALK5)

Published:2009-09-08 Issue:23 Volume:52 Page:7901-7905
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Goldberg Frederick W.¹,Ward Richard A.¹,Powell Steven J.¹,Debreczeni Judit É.¹,Norman Richard A.¹,Roberts Nicola J.¹,Dishington Allan P.¹,Gingell Helen J.¹,Wickson Kate F.¹,Roberts Andrew L.¹

Affiliation:

1. AstraZeneca, Mereside, Alderley Park, Macclesfield SK10 4TG, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900807w

Reference24 articles.

1. Divergence and convergence of TGF-?/BMP signaling

2. Alterations in components of the TGF-β superfamily signaling pathways in human cancer

3. Transforming Growth Factor–β Regulates Mammary Carcinoma Cell Survival and Interaction with the Adjacent Microenvironment

4. Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)

5. Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors

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