Developing Biodegradable Lipid Nanoparticles for Intracellular mRNA Delivery and Genome Editing
Author:
Affiliation:
1. Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, Massachusetts 02155, United States
2. School of Medicine & Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts 02111, United States
Funder
National Institutes of Health
Publisher
American Chemical Society (ACS)
Subject
General Medicine,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.1c00500
Reference53 articles.
1. Imidazole‐Based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes
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3. Protein and mRNA Delivery Enabled by Cholesteryl‐Based Biodegradable Lipidoid Nanoparticles
4. Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3
5. mRNA-based therapeutics — developing a new class of drugs
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