An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX-Reference-Cited by-同舟云学术

An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX

Published:2020-11-24 Issue:3 Volume:54 Page:618-631
ISSN:0001-4842
Container-title:Accounts of Chemical Research
language:en
Short-container-title:Acc. Chem. Res.

Author:

Long Marcus J. C.¹,Rogg Chloé²,Aye Yimon²^ORCID

Affiliation:

1. Department of Molecular Biology, University of Geneva, 30 quai Ernest-Ansermet, 1211 Geneva, Switzerland

2. Institute of Chemical Sciences and Engineering (ISIC), Swiss Federal Institute of Technology Lausanne (EPFL), Route Cantonale, 1015 Lausanne, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Novartis Foundation

?cole Polytechnique F?d?rale de Lausanne

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

General Medicine,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.0c00537

Reference71 articles.

1. T-REX on-demand redox targeting in live cells

2. Akt3 is a privileged first responder in isozyme-specific electrophile response

3. Ube2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses

4. Precision Targeting of pten-Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing

5. How to improve R&D productivity: the pharmaceutical industry's grand challenge

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