Chemical Versatility in Catalysis and Inhibition of the Class IIb Histone Deacetylases
Author:
Affiliation:
1. Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States
Funder
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.3c00801
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1. Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
2. Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
3. X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10
4. Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6
5. ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS
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