Enantioselective Total Synthesis of Pladienolide B: A Potent Spliceosome Inhibitor
Author:
Affiliation:
1. Department of Chemistry and Department of Medicinal Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol301886g
Reference32 articles.
1. Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 I. Taxonomy, Fermentation, Isolation and Screening
2. Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 II. Physico-chemical Properties and Structure Elucidation
3. Stereochemistry of Pladienolide B
4. Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 III. In Vitro and In Vivo Antitumor Activities
5. Splicing factor SF3b as a target of the antitumor natural product pladienolide
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