Density Functional Theory Study on the Formation of Reactive Benzoquinone Imines by Hydrogen Abstraction
Author:
Affiliation:
1. Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci500653b
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1. Acetaminophen Hepatotoxicity
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3. Acetaminophen Binds to Mouse Hepatic and Renal DNA at Human Therapeutic Doses
4. Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose
5. Hepatotoxic metabolic activation of paracetamol and its derivatives phenacetin and benorilete: Oxygenation or electron transfer?
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