1-Substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones Endowed with Dual DNA-PK/PI3-K Inhibitory Activity-Reference-Cited by-同舟云学术

1-Substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones Endowed with Dual DNA-PK/PI3-K Inhibitory Activity

Published:2013-08-01 Issue:16 Volume:56 Page:6386-6401
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cano Céline¹,Saravanan Kappusamy¹,Bailey Chris²,Bardos Julia²,Curtin Nicola J.³,Frigerio Mark²,Golding Bernard T.¹,Hardcastle Ian R.¹,Hummersone Marc G.²,Menear Keith A.²,Newell David R.³,Richardson Caroline J.²,Shea K.²⁴,Smith Graeme C. M.²⁴,Thommes Pia²⁴,Ting Attilla⁴,Griffin Roger J.¹

Affiliation:

1. Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU, United Kingdom

2. KuDOS Pharmaceuticals, Ltd., 410 Cambridge Science Park, Milton Road, Cambridge, CB4 0PE, United Kingdom

3. Newcastle Cancer Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom

4. AstraZeneca, Oncology Innovative Medicines, Alderley Park, Macclesfield, Cheshire, SK10 4TG, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400915j

Reference35 articles.

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4. Smith, G. C. M.; Jackson, S. P.Handbook of Cell Signaling;Elsevier Academic Press:New York, 2003; Vol.1, pp557–561.

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