Spiro- and Dispiro-1,2-dioxolanes: Contribution of Iron(II)-Mediated One-Electron vs Two-Electron Reduction to the Activity of Antimalarial Peroxides-Reference-Cited by-同舟云学术

Spiro- and Dispiro-1,2-dioxolanes: Contribution of Iron(II)-Mediated One-Electron vs Two-Electron Reduction to the Activity of Antimalarial Peroxides

Published:2007-10-20 Issue:23 Volume:50 Page:5840-5847
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Xiaofang¹,Dong Yuxiang¹,Wittlin Sergio¹,Creek Darren¹,Chollet Jacques¹,Charman Susan A.¹,Santo Tomas Josefina¹,Scheurer Christian¹,Snyder Christopher¹,Vennerstrom Jonathan L.¹

Affiliation:

1. College of Pharmacy, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, Nebraska, Swiss Tropical Institute, Socinstrasse 57, CH-4002 Basel, Switzerland, and Centre for Drug Candidate Optimisation, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0707673

Reference42 articles.

1. Synthetic peroxides as antimalarials

2. Dispiro-1,2,4-trioxane Analogues of a Prototype Dispiro-1,2,4-trioxolane: Mechanistic Comparators for Artemisinin in the Context of Reaction Pathways with Iron(II)

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