Design and Synthesis of Potent C2-Symmetric Diol-Based HIV-1 Protease Inhibitors: Effects of Fluoro Substitution-Reference-Cited by-同舟云学术

Design and Synthesis of Potent C2-Symmetric Diol-Based HIV-1 Protease Inhibitors: Effects of Fluoro Substitution

Published:2001-08-15 Issue:19 Volume:44 Page:3083-3091
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pyring David¹,Lindberg Jimmy¹,Rosenquist Åsa¹,Zuccarello Guido¹,Kvarnström Ingemar¹,Zhang Hong¹,Vrang Lotta¹,Unge Torsten¹,Classon Bjorn¹,Hallberg Anders¹,Samuelsson Bertil¹

Affiliation:

1. Department of Chemistry, Linköping University, SE-581 83 Linköping, Sweden, Department of Cell and Molecular Biology, BMC, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden, Medivir AB, Lunastigen 7, SE-141 44 Huddinge, Sweden, Department of Organic Pharmaceutical Chemistry, Uppsala University, BMC, Box 574, SE-751 23 Uppsala, Sweden, and Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm001134q

Reference43 articles.

1. Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

2. Isolation of Human T-Cell Leukemia Virus in Acquired Immune Deficiency Syndrome (AIDS)

3. Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

4. Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity

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