Dihydrofolate Reductase Mutant with Exceptional Resistance to Methotrexate but Not to Trimetrexate-Reference-Cited by-同舟云学术

Dihydrofolate Reductase Mutant with Exceptional Resistance to Methotrexate but Not to Trimetrexate

Published:2003-06-07 Issue:14 Volume:46 Page:2816-2818
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pineda Pamela¹,Kanter Aaron¹,McIvor R. Scott¹,Benkovic Stephen J.¹,Rosowsky Andre¹,Wagner Carston R.¹

Affiliation:

1. Departments of Medicinal Chemistry and of Genetics and Development, University of Minnesota, Minneapolis, Minnesota 55455, Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, and Department of Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm034057i

Reference12 articles.

1. Dihydrofolate reductase as a therapeutic target

2. The clinical pharmacology of methotrexate

3. Etoposide (VP-16) with prednisone and vincristine for the treatment of refractory acute lymphoblastic leukemia.

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A trimethoprim derivative impedes antibiotic resistance evolution;Nature Communications;2021-05-19

2. In silico studies on potential MCF-7 inhibitors: a combination of pharmacophore and 3D-QSAR modeling, virtual screening, molecular docking, and pharmacokinetic analysis;Journal of Biomolecular Structure and Dynamics;2016-07-12

3. Chemically Self-Assembled Antibody Nanostructures as Potential Drug Carriers;Molecular Pharmaceutics;2012-10-16

4. Synthesis of 2,4-Diaminoquinazolines and Tricyclic Quinazolines by Cascade Reductive Cyclization of Methyl N-Cyano-2-nitrobenzimidates;The Journal of Organic Chemistry;2012-02-24

5. Self-Assembly of Antibodies by Chemical Induction;Angewandte Chemie International Edition;2008-12-15