Irreversible enzyme inhibitors. CXX. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-substituted 2,3-diamino-5-phenylpyrimidines with tissue specificity
Author:
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm00309a019
Cited by 18 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Structure-activity relationships of dihydrofolated reductase inhibitors;Chemical Reviews;1984-08-01
2. Irreversible enzyme inhibitors. CLXXV. Irreversible inhibition of purifed dihydrofolic reductase;Journal of Medicinal Chemistry;1970-11
3. Irreversible enzyme inhibitors. CLXXIII. Cure of Walker 256 ascites by reversible and irreversible inhibitors of dihydrofolic reductase derived from 1-(substituted-phenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine;Journal of Medicinal Chemistry;1970-11
4. Irreversible enzyme inhibitors. CLVIII. Effect of bridge modification on the selective irreversible inhibition of a dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. II;Journal of Medicinal Chemistry;1969-07
5. Irreversible enzyme inhibitors. CLVII. Effect of bridge modification on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. I;Journal of Medicinal Chemistry;1969-07
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