1-(2-Nitrophenyl)thiosemicarbazides: A Novel Class of Potent, Orally Active Non-Peptide Antagonist for the Bradykinin B2 Receptor-Reference-Cited by-同舟云学术

1-(2-Nitrophenyl)thiosemicarbazides: A Novel Class of Potent, Orally Active Non-Peptide Antagonist for the Bradykinin B2 Receptor

Published:2000-02-12 Issue:5 Volume:43 Page:769-771
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dziadulewicz Edward K.¹,Ritchie Timothy J.¹,Hallett Allan¹,Snell Christopher R.¹,Ko Soo Y.¹,Wrigglesworth Roger¹,Hughes Glyn A.¹,Dunstan Andrew R.¹,Bloomfield Graham C.¹,Drake Gillian S.¹,Brown Michael C.¹,Lee Wai¹,Burgess Gillian M.¹,Davis Clare¹,Yaqoob Mohammed¹,Perkins Martin N.¹,Campbell Elizabeth A.¹,Davis Andrew J.¹,Rang Humphrey P.¹

Affiliation:

1. Departments of Medicinal Chemistry, Biology, and Pharmacology, Novartis Institute for Medical Sciences, 5 Gower Place, London WC1E 6BN, England

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991155o

Reference17 articles.

1. Bradykinin receptor antagonists

2. Competitive antagonists of bradykinin

3. Hoe 140 a new potent and long acting bradykinin-antagonist: in vivo studies

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