Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes-Reference-Cited by-同舟云学术

Discovery of a Highly Potent, Nonabsorbable Apical Sodium-Dependent Bile Acid Transporter Inhibitor (GSK2330672) for Treatment of Type 2 Diabetes

Published:2013-06-06 Issue:12 Volume:56 Page:5094-5114
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Yulin¹,Aquino Christopher J.¹,Cowan David J.¹,Anderson Don L.¹,Ambroso Jeff L.¹,Bishop Michael J.¹,Boros Eric E.¹,Chen Lihong¹,Cunningham Alan¹,Dobbins Robert L.¹,Feldman Paul L.¹,Harston Lindsey T.¹,Kaldor Istvan W.¹,Klein Ryan¹,Liang Xi¹,McIntyre Maggie S.¹,Merrill Christine L.¹,Patterson Kristin M.¹,Prescott Judith S.¹,Ray John S.¹,Roller Shane G.¹,Yao Xiaozhou¹,Young Andrew¹,Yuen Josephine¹,Collins Jon L.¹

Affiliation:

1. GlaxoSmithKline Research & Development, Five Moore Drive, Research Triangle Park, North Carolina 27709, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400459m

Reference23 articles.

1. Recent facts about diabetes can be found via the Internet at the World Health Organization website:Diabetes,Fact Sheet no. 312:World Health Organization:Geneva,March, 2013; http://www.who.int/mediacentre/factsheets/fs312/en/.

2. Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach

3. Incretins and other peptides in the treatment of diabetes

4. The incretin system and its role in type 2 diabetes mellitus

5. The entero-insular axis in type 2 diabetes - incretins as therapeutic agents

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