Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent

Published:2001-03-10 Issue:8 Volume:44 Page:1217-1230
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Larsen Scott D.¹,Connell Mark A.¹,Cudahy Michele M.¹,Evans Bruce R.¹,May Paul D.¹,Meglasson Martin D.¹,O'Sullivan Theresa J.¹,Schostarez Heinrich J.¹,Sih John C.¹,Stevens F. Craig¹,Tanis Steven P.¹,Tegley Christopher M.¹,Tucker John A.¹,Vaillancourt Valerie A.¹,Vidmar Thomas J.¹,Watt William¹,Yu Jen H.¹

Affiliation:

1. Departments of Medicinal Chemistry, Pharmacology, Structural, Analytical and Medicinal Chemistry, and Research Biostatistics, Pharmacia Corporation, 301 Henrietta Street, Kalamazoo, Michigan 49007

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000095f

Reference60 articles.

1. The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

2. Slow Glucose Removal Rate and Hyperinsulinemia Precede the Development of Type II Diabetes in the Offspring of Diabetic Parents

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