Structural Analogues of Smoothened Intracellular Loops as Potent Inhibitors of Hedgehog Pathway and Cancer Cell Growth-Reference-Cited by-同舟云学术

Structural Analogues of Smoothened Intracellular Loops as Potent Inhibitors of Hedgehog Pathway and Cancer Cell Growth

Published:2007-08-08 Issue:18 Volume:50 Page:4534-4538
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Remsberg Jarrett R.¹,Lou Hong¹,Tarasov Sergey G.¹,Dean Michael¹,Tarasova Nadya I.¹

Affiliation:

1. Molecular Aspects of Drug Design Section, Structural Biophysics Laboratory, National Cancer InstituteFrederick, Frederick, Maryland 21702, Human Genetics Section, Laboratory of Genomic Diversity, National Cancer InstituteFrederick, Frederick, Maryland 21702, and Biophysics Resource, Structural Biophysics Laboratory, National Cancer InstituteFrederick, P.O. Box B, Frederick, Maryland 21702

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0705657

Reference43 articles.

1. Tissue repair and stem cell renewal in carcinogenesis

2. Hedgehog signaling pathway as a therapeutic target in breast cancer

3. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma;Biochemical Pharmacology;2021-08

2. Genetic and Epigenetic Regulation of the Smoothened Gene (SMO) in Cancer Cells;Cancers;2020-08-08

3. Deciphering the Allosteric Effect of Antagonist Vismodegib on Smoothened Receptor Deactivation Using Metadynamics Simulation;Frontiers in Chemistry;2019-06-04

4. Therapeutic Potential of Targeting ß-Arrestin;Frontiers in Pharmacology;2019-03-06

5. Peptide Lipidation – A Synthetic Strategy to Afford Peptide Based Therapeutics;Peptides and Peptide-based Biomaterials and their Biomedical Applications;2017