A Concise Approach to 2-Azabicyclo[3.3.1]nonane Derivatives from an Acyclic Precursor
Author:
Affiliation:
1. Departamento de Química Orgánica II, Facultad de Ciencia y Tecnología, Universidad del País Vasco, Apartado 644, 48080 Bilbao, Spain jm.aurrecoechea@ehu.es
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo051471c
Reference11 articles.
1. See also Díez, A.; Castells, J.; Forns, P.; Rubiralta, M.; Grierson, D. S.; Husson, H.P.; Solans, X.; Font-Bardía, M.Tetrahedron1994,50, 6585−6602 for a different approach to related α-cyanopiperidines that also suffers from regioselectivity problems.
2. Stereocontrolled synthesis of polysubstituted piperidines from vinylogous Mannich adducts and aldehydes
3. A stereocontrolled synthesis of (.+-.)-emetine and (.+-.)-protoemetinol by intramolecular michael reaction.
4. Synthesis of 2,3-disubstituted pyrrolidines by intramolecular addition of α-aminoalkyl radicals to electron deficient C C bonds
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