Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)-Reference-Cited by-同舟云学术

Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)

Published:2010-04-20 Issue:9 Volume:53 Page:3814-3830
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Watterson Scott H.¹,Xiao Zili¹,Dodd Dharmpal S.¹,Tortolani David R.¹,Vaccaro Wayne¹,Potin Dominique²,Launay Michele²,Stetsko Dawn K.¹,Skala Stacey¹,Davis Patric M.¹,Lee Deborah¹,Yang Xiaoxia¹,McIntyre Kim W.¹,Balimane Praveen¹,Patel Karishma¹,Yang Zheng¹,Marathe Punit¹,Kadiyala Pathanjali¹,Tebben Andrew J.¹,Sheriff Steven¹,Chang ChiehYing Y.¹,Ziemba Theresa¹,Zhang Huiping¹,Chen Bang-Chi¹,DelMonte Albert J.¹,Aranibar Nelly¹,McKinnon Murray¹,Barrish Joel C.¹,Suchard Suzanne J.¹,Murali Dhar T. G.¹

Affiliation:

1. Bristol-Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543

2. Cerep, 19 Avenue du Quebec, 91951 Courtaboeuf cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100348u

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