Robust and Comprehensive Targeted Metabolomics Method for Quantification of 50 Different Primary, Secondary, and Sulfated Bile Acids in Multiple Biological Species (Human, Monkey, Rabbit, Dog, and Rat) and Matrices (Plasma and Urine) Using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS) Analysis
Author:
Affiliation:
1. Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States
2. Bioanalytical Department, Covance Laboratories, Inc., 3301 Kinsman Blvd, Madison, Wisconsin 53704, United States
Publisher
American Chemical Society (ACS)
Subject
Spectroscopy,Structural Biology
Link
https://pubs.acs.org/doi/pdf/10.1021/jasms.0c00435
Reference44 articles.
1. Clinical Utility of Bile Acid Sequestrants in the Treatment of Dyslipidemia: A Scientific Review
2. Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
3. Bile Acids and the Membrane Bile Acid Receptor TGR5—Connecting Nutrition and Metabolism
4. A gut–brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus
5. Fifty years of advances in bile acid synthesis and metabolism
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