Optimization of dropletProbe-Mass Spectrometry for Whole-Body Tissue Distribution Analysis of Drug-Like Molecules-Reference-Cited by-同舟云学术

Optimization of dropletProbe-Mass Spectrometry for Whole-Body Tissue Distribution Analysis of Drug-Like Molecules

Published:2020-06-15 Issue:12 Volume:31 Page:2558-2562
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Chen Bingming¹^ORCID,Vavrek Marissa¹,Cancilla Mark T.¹

Affiliation:

1. Department of Pharmacokinetics, Pharmacodynamics & Drug Metabolism (PPDM), Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

https://pubs.acs.org/doi/pdf/10.1021/jasms.0c00168

Reference15 articles.

1. Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

2. MALDI imaging facilitates new topical drug development process by determining quantitative skin distribution profiles

3. From Whole-body Sections Down to Cellular Level, Multiscale Imaging of Phospholipids by MALDI Mass Spectrometry

4. Label-free MS imaging from drug discovery to preclinical development

5. Liquid Microjunction Surface Sampling Coupled with High-Pressure Liquid Chromatography−Electrospray Ionization-Mass Spectrometry for Analysis of Drugs and Metabolites in Whole-Body Thin Tissue Sections

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2. Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization;Analytica Chimica Acta;2022-11

3. Development and Application of DropletProbe Mass Spectrometry for Examining Biodistribution of Therapeutics;Methods in Molecular Biology;2021-12-14