Carba-LNA-5MeC/A/G/T Modified Oligos Show Nucleobase-Specific Modulation of 3′-Exonuclease Activity, Thermodynamic Stability, RNA Selectivity, and RNase H Elicitation: Synthesis and Biochemistry-Reference-Cited by-同舟云学术

Carba-LNA-5MeC/A/G/T Modified Oligos Show Nucleobase-Specific Modulation of 3′-Exonuclease Activity, Thermodynamic Stability, RNA Selectivity, and RNase H Elicitation: Synthesis and Biochemistry

Published:2011-05-04 Issue:11 Volume:76 Page:4408-4431
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Upadhayaya RamShankar¹,Deshpande Sachin Gangadhar¹,Li Qing²,Kardile Ramakant Asaram¹,Sayyed Aftab Yusuf¹,Kshirsagar Eknath Kamalakar¹,Salunke Rahul Vilas¹,Dixit Shailesh Satish¹,Zhou Chuanzheng²,Földesi András²,Chattopadhyaya Jyoti²

Affiliation:

1. Institute of Molecular Medicine, International Biotech Park, Genesis Campus, Phase II Opp Infosys, Tal Mulshi, Hinjewadi, Pune 411 057, India

2. Program of Bioorganic Chemistry, Institute of Cell and Molecular Biology, Biomedical Centre, Uppsala University, SE-75123 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo200073q

Reference65 articles.

1. The promises and pitfalls of RNA-interference-based therapeutics

2. Antisense technologies. Improvement through novel chemical modifications