Efficient Delivery of Bcl-2-Targeted siRNA Using Cationic Polymer Nanoparticles: Downregulating mRNA Expression Level and Sensitizing Cancer Cells to Anticancer Drug-Reference-Cited by-同舟云学术

Efficient Delivery of Bcl-2-Targeted siRNA Using Cationic Polymer Nanoparticles: Downregulating mRNA Expression Level and Sensitizing Cancer Cells to Anticancer Drug

Published:2008-12-15 Issue:1 Volume:10 Page:41-48
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Beh Cyrus W.¹,Seow Wei Yang¹,Wang Yong¹,Zhang Ying¹,Ong Zhan Yuin¹,Ee Pui Lai Rachel¹,Yang Yi-Yan¹

Affiliation:

1. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, Singapore 138669, Singapore, Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore, 117543, Singapore, and Department of Immunology, Faculty of Medicine Imperial College London, Hammersmith Hospital Du Cane Road London, W120NN, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/bm801109g

Reference31 articles.

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3. RNA interference in cancer

4. Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells

5. Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer

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