Layer-by-Layer Assembly of Polymeric Nanoparticles with Heparin-RBD Complexes as an Adjuvant for SARS-CoV-2 Protein-Based Vaccines

Author:

Delechiave Giovanne1ORCID,de Oliveira Silva Mariangela2ORCID,de Castro-Amarante Maria Fernanda2ORCID,Mallaupoma Camarena Denisse Esther13ORCID,Venceslau-Carvalho Alexia A.24ORCID,Ferreira Luís Carlos de Souza2ORCID,Catalani Luiz Henrique1ORCID

Affiliation:

1. Department of Fundamental Chemistry, Institute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, 26077, 05508-000 São Paulo, Brazil

2. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1374, 05508-000 São Paulo, Brazil

3. Clinical Chemistry & Toxicology Department, School of Pharmaceutical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 580, 05508-000 São Paulo, Brazil

4. Scientific Platform Pasteur USP, University of São Paulo, Av. Prof. Lucio Martins Rodrigues, 370, Bl. A, 05508-020 São Paulo, Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Chemical Society (ACS)

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