The “Latent Membrane Permeability” Concept: QSPR Analysis of Inter/Intralaboratorically Variable Caco-2 Permeability
Author:
Affiliation:
1. Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan
Publisher
American Chemical Society (ACS)
Subject
Computational Theory and Mathematics,Computer Science Applications,Information Systems,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci010317y
Reference20 articles.
1. Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985).
2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
3. High-throughput approaches for evaluating absorption, distribution, metabolism and excretion properties of lead compounds
4. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics
5. Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability
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