Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody

Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody–Drug Conjugates

Published:2014-02-12 Issue:3 Volume:25 Page:569-578
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Dennler Patrick¹,Chiotellis Aristeidis²,Fischer Eliane¹,Brégeon Delphine³,Belmant Christian³,Gauthier Laurent³,Lhospice Florence³,Romagne François³,Schibli Roger¹²

Affiliation:

1. Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland

2. Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8092 Zurich, Switzerland

3. Innate-Pharma SA, 13276 Marseille, France

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc400574z

Reference37 articles.

1. Investigational antibody drug conjugates for solid tumors

2. Antibody-Drug Conjugates in Cancer Therapy

3. The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics

4. Antibody–drug conjugates: Basic concepts, examples and future perspectives

5. Antibody-Drug Conjugates for the Treatment of Cancer

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