Abyssomicin 2 Reactivates Latent HIV-1 by a PKC- and HDAC-Independent Mechanism-Reference-Cited by-同舟云学术

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Abyssomicin 2 Reactivates Latent HIV-1 by a PKC- and HDAC-Independent Mechanism

Published:2015-01-05 Issue:2 Volume:17 Page:262-265
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

León Brian¹,Navarro Gabriel¹,Dickey Bailey J.¹,Stepan George²,Tsai Angela²,Jones Gregg S.²,Morales Monica E.¹,Barnes Tiffany²,Ahmadyar Shekeba²,Tsiang Manuel²,Geleziunas Romas²,Cihlar Tomas²,Pagratis Nikos²,Tian Yang²,Yu Helen²,Linington Roger G.¹

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, Santa Cruz, 1156 High Street, Santa Cruz, California 95064, United States

2. Department of Biology, Gilead Sciences, Inc. 333 Lakeside Drive, Foster City, California 94404, United States

Funder

National Science Foundation

Gilead Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol503349y

Reference27 articles.

1. Non-AIDS-defining malignancies among HIV-infected patients in the highly active antiretroviral therapy era

2. Cardiovascular Risks of Antiretroviral Therapies

3. The Challenge of Finding a Cure for HIV Infection

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1. An in silico design of antivirus nickel (II) complexes as therapeutic drug candidates;Indian Journal of Chemistry;2023-06-19

2. First total synthesis of type II abyssomicins: (±)-abyssomicin 2 and (±)-neoabyssomicin B;Organic & Biomolecular Chemistry;2023

3. Potential HIV latency-reversing agents with STAT1-activating activity from the leaves of Wikstroemia chamaedaphne;Phytochemistry;2022-11

4. Virtual screening and molecular dynamics simulation study of abyssomicins as potential inhibitors of COVID‐19 virus main protease and spike protein;Journal of Biomolecular Structure and Dynamics;2022-10-27

5. Abyssomicin W and Neoabyssomicin B are potential inhibitors of New Delhi Metallo-β-Lactamase-1 (NDM -1): A computational approach;Pharmacognosy Magazine;2022

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