Development of Novel EDG3 Antagonists Using a 3D Database Search and Their Structure−Activity Relationships-Reference-Cited by-同舟云学术

Development of Novel EDG3 Antagonists Using a 3D Database Search and Their Structure−Activity Relationships

Published:2002-09-13 Issue:21 Volume:45 Page:4629-4638
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Koide Yuuki¹,Hasegawa Takeshi¹,Takahashi Atsuo¹,Endo Akira¹,Mochizuki Naoki¹,Nakagawa Masako¹,Nishida Atsushi¹

Affiliation:

1. Drug Research Department, Tokyo Research Laboratories, TOA EIYO Ltd., 2-293-3 Amanuma, Saitama 330-0834, Japan, Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoicho, Inage, Chiba 263-8522, Japan, Drug Research Department, Fukushima Research Laboratories, TOA EIYO Ltd., 1 Tanaka, Yuno, Iizaka, Fukushima 960-0280, Japan, and Department of Structural Analysis, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020080c

Reference37 articles.

1. FDA "Reform"?

2. Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

3. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

4. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

5. Molecular Cloning, Tissue-Specific Expression, and Chromosomal Localization of a Novel Nerve Growth Factor-Regulated G-Protein-Coupled Receptor, nrg-1

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