Allylic Alcohol Transposition by Ortho Ester-Initiated Carbonate Extension. Synthesis of the Vasodilator 11(R),12(S),15(S)-Trihydroxyeicosa- 5(Z),8(Z),13(E)-trienoic Acid
Author:
Affiliation:
1. Alcon Research, Ltd., Chemical Preparations Research, 6201 South Freeway, R8-6, Fort Worth, Texas 76134
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol0608808
Reference30 articles.
1. Asymmetric synthesis of the stereoisomers of 11,12,15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid, a potent endothelium-derived vasodilator
2. Transformation of 15-hete to 14,15-dihydroxyeicosatrienoic acid and 11,14,15- and 13,14,15-trihydroxyeicosatrienoic acid
3. 2-Substituted tetrahydrofurans of known absolute stereochemistry by ScN' chirality transfer
4. Synthesis of Cryptophycin 52 Using the Sharpless Asymmetric Dihydroxylation: Diol to Epoxide Transformation Optimized for a Base-Sensitive Substrate
5. Stereospecific Synthesis of Cryptophycin 1
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