Broadening the Scope of Sapofection: Cationic Peptide-Saponin Conjugates Improve Gene Delivery <i>In Vitro</i> and <i>In Vivo</i>-Reference-Cited by-同舟云学术

Broadening the Scope of Sapofection: Cationic Peptide-Saponin Conjugates Improve Gene Delivery In Vitro and In Vivo

Published:2024-07-06 Issue:28 Volume:16 Page:36095-36105
ISSN:1944-8244
Container-title:ACS Applied Materials & Interfaces
language:en
Short-container-title:ACS Appl. Mater. Interfaces

Author:

Kolster Meike¹,Sonntag Alexander¹,Weise Christoph²,Correa Juan³,Fuchs Hendrik⁴^ORCID,Walther Wolfgang⁵,Fernandez-Megia Eduardo³^ORCID,Weng Alexander¹

Affiliation:

1. Institut für Pharmazie, Freie Universität Berlin, Königin-Luise-Straße 2-4, Berlin 14195, Germany

2. Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, Berlin 14195, Germany

3. Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Jenaro de la Fuente s/n, Santiago de Compostela 15782, Spain

4. Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charité − Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, Berlin 13353, Germany

5. Experimental Pharmacology & Oncology Berlin-Buch GmbH, Robert-Rössle-Str. 10, Berlin 13125, Germany

Funder

European Regional Development Fund

Xunta de Galicia

Horizon 2020 Framework Programme

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsami.4c05846

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3. U.S. Food & Drug Administration, Approved Cellular and Gene Therapy Products, https://www.fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/approved-cellular-and-gene-therapy-products. 2024.

4. Viral vector platforms within the gene therapy landscape

5. Changing trends in the development of AAV-based gene therapies: a meta-analysis of past and present therapies