In Situ Heparan Sulfate-Induced Peptide Self-Assembly to Overcome the Cell Surface Glycocalyx Barrier for Cancer Treatment

Author:

Pei Pengfei1,Chen Long1ORCID,Guan Xinyao1,Wei Peng2ORCID,Kang Xiaoxu3,Gong Lili3ORCID,Liu Lihong3,Guo Wenxu1,Gu Renji1,Wang Lixin4,Zhao Chuanke4,Liang Jun F.5,Luo Shi-Zhong1

Affiliation:

1. State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China

2. School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China

3. Institute of Medical Science, China-Japan Friendship Hospital, Beijing 100029, China

4. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital & Institute, Beijing 100142, China

5. Department of Chemistry, Chemical Biology, and Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey 07030, United States

Funder

National Key Research and Development Program of China

China Postdoctoral Science Foundation

China-Japan Friendship Hospital

Beijing University of Chemical Technology

Natural Science Foundation of Beijing Municipality

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing

Publisher

American Chemical Society (ACS)

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